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- Q & A: Current
Biology, Vol.
13, No. 13. (1
July 2003),
pp.
R501-R502.Alex
ander
Varshavsky is
Smits
Professor of
Cell Biology
at the
California
Institute of
Technology. He
moved to
Caltech in
1992, after 15
years at the
MIT's
Department of
Biology. He
was born and
educated in
Russia, and
was 30 at the
time of his
emigration to
the U.S. in
1977. In
Russia, and
for a while at
MIT, he
studied the
structure and
replication of
chromosomes.
Over the last
24 years, the
work of his
laboratory
focused on the
ubiquitin
system and
closely
related
fields. He is
a member of
the U.S.
National
Academy of
Sciences, and
has received
the Gairdner
Award, the
Lasker Award,
the General
Motors Sloan
Prize, the
Wolf Prize,
the Horwitz
Prize, and the
Wilson Medal.
Source: Current Biology, Vol. 13, No. 13. (1 July 2003), pp. R501-R502. - Integrating
scientific
cultures: Mol Syst Biol,
Vol. 3 (17
April 2007)
Source: Mol Syst Biol, Vol. 3 (17 April 2007) - Nature's guide
for mentors: Nature, Vol.
447, No. 7146.
(14 June
2007), pp.
791-797.
Source: Nature, Vol. 447, No. 7146. (14 June 2007), pp. 791-797. - Electric Field
Effect in
Atomically
Thin Carbon
Films: Science, Vol.
306, No. 5696.
(22 October
2004), pp.
666-669.We
describe
monocrystallin
e graphitic
films, which
are a few
atoms thick
but are
nonetheless
stable under
ambient
conditions,
metallic, and
of remarkably
high quality.
The films are
found to be a
two-dimensiona
l semimetal
with a tiny
overlap
between
valence and
conductance
bands, and
they exhibit a
strong
ambipolar
electric field
effect such
that electrons
and holes in
concentrations
up to 1013 per
square
centimeter and
with
room-temperatu
re mobilities
of [~]10,000
square
centimeters
per
volt-second
can be induced
by applying
gate voltage.
10.1126/scienc
e.1102896
Source: Science, Vol. 306, No. 5696. (22 October 2004), pp. 666-669. - Measurement of
the Elastic
Properties and
Intrinsic
Strength of
Monolayer
Graphene: Science, Vol.
321, No. 5887.
(18 July
2008), pp.
385-388.We
measured the
elastic
properties and
intrinsic
breaking
strength of
free-standing
monolayer
graphene
membranes by
nanoindentatio
n in an atomic
force
microscope.
The
force-displace
ment behavior
is interpreted
within a
framework of
nonlinear
elastic
stress-strain
response, and
yields second-
and
third-order
elastic
stiffnesses of
340 newtons
per meter (N
m-1) and -690
Nm-1,
respectively.
The breaking
strength is 42
N m-1 and
represents the
intrinsic
strength of a
defect-free
sheet. These
quantities
correspond to
a Young's
modulus of E =
1.0
terapascals,
third-order
elastic
stiffness of D
= -2.0
terapascals,
and intrinsic
strength of
sigmaint = 130
gigapascals
for bulk
graphite.
These
experiments
establish
graphene as
the strongest
material ever
measured, and
show that
atomically
perfect
nanoscale
materials can
be
mechanically
tested to
deformations
well beyond
the linear
regime.
10.1126/scienc
e.1157996
Source: Science, Vol. 321, No. 5887. (18 July 2008), pp. 385-388.
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